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Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen

Naturally occurring fragments of the abundant semen proteins prostatic acid phosphatase (PAP) and semenogelins form amyloid fibrils in vitro. These fibrils boost HIV infection and may play a key role in the spread of the AIDS pandemic. However, the presence of amyloid fibrils in semen remained to be...

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Detalles Bibliográficos
Autores principales: Usmani, Shariq M., Zirafi, Onofrio, Müller, Janis, Sandi-Monroy, Nathallie, Yadav, Jay K., Meier, Christoph, Weil, Tanja, Roan, Nadia R., Greene, Warner C., Walther, Paul, Nilsson, K. Peter R., Hammarström, Per, Wetzel, Ronald, Pilcher, Christopher D., Gagsteiger, Friedrich, Fändrich, Marcus, Kirchhoff, Frank, Münch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129123/
https://www.ncbi.nlm.nih.gov/pubmed/24691351
http://dx.doi.org/10.1038/ncomms4508