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Objective cardiac markers and cerebrovascular lesions in Indian seniors
Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Atlantis Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129368/ https://www.ncbi.nlm.nih.gov/pubmed/25107661 http://dx.doi.org/10.1016/j.jegh.2014.02.003 |
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author | Charles, Stephanie H. Tow, Amanda C. Verghese, Joe |
author_facet | Charles, Stephanie H. Tow, Amanda C. Verghese, Joe |
author_sort | Charles, Stephanie H. |
collection | PubMed |
description | Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p < .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas. |
format | Online Article Text |
id | pubmed-4129368 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Atlantis Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-41293682015-09-01 Objective cardiac markers and cerebrovascular lesions in Indian seniors Charles, Stephanie H. Tow, Amanda C. Verghese, Joe J Epidemiol Glob Health Article Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p < .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas. Atlantis Press 2014 2014-03-29 /pmc/articles/PMC4129368/ /pubmed/25107661 http://dx.doi.org/10.1016/j.jegh.2014.02.003 Text en © 2014 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Charles, Stephanie H. Tow, Amanda C. Verghese, Joe Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title | Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title_full | Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title_fullStr | Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title_full_unstemmed | Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title_short | Objective cardiac markers and cerebrovascular lesions in Indian seniors |
title_sort | objective cardiac markers and cerebrovascular lesions in indian seniors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129368/ https://www.ncbi.nlm.nih.gov/pubmed/25107661 http://dx.doi.org/10.1016/j.jegh.2014.02.003 |
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