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Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels
Many genetic variants associated with human disease have been found to be associated with alterations in mRNA expression. Although it is commonly assumed that mRNA expression changes will lead to consequent changes in protein levels, methodological challenges have limited our ability to test the deg...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129400/ https://www.ncbi.nlm.nih.gov/pubmed/25087611 http://dx.doi.org/10.1016/j.ajhg.2014.07.005 |