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S100B protein in serum is elevated after global cerebral ischemic injury

BACKGROUND: S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of global cerebral ischemic injury will be dramatically increased. Ischemic brain injury may elevate the level of serum S100B protein and the severity of brain damage. METHODS: This article is a critical an...

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Autores principales: Sun, Bao-di, Liu, Hong-mei, Nie, Shi-nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Affiliated Hospital of Zhejiang University School of Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129854/
https://www.ncbi.nlm.nih.gov/pubmed/25215112
http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.001
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author Sun, Bao-di
Liu, Hong-mei
Nie, Shi-nan
author_facet Sun, Bao-di
Liu, Hong-mei
Nie, Shi-nan
author_sort Sun, Bao-di
collection PubMed
description BACKGROUND: S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of global cerebral ischemic injury will be dramatically increased. Ischemic brain injury may elevate the level of serum S100B protein and the severity of brain damage. METHODS: This article is a critical and descriptive review on S100B protein in serum after ischemic brain injury. We searched Pubmed database with key words or terms such as “S100B protein”, “cardiac arrest”, “hemorrhagic shock” and “ischemia reperfusion injury” appeared in the last five years. RESULTS: S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of ischemic brain injury will be dramatically increased. Ischemic brain injury elevated the level of serum S100B protein, and the severity of brain damage. CONCLUSION: The level of S100B protein in serum is elevated after ischemic brain injury, but its mechanism is unclear.
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spelling pubmed-41298542014-09-11 S100B protein in serum is elevated after global cerebral ischemic injury Sun, Bao-di Liu, Hong-mei Nie, Shi-nan World J Emerg Med Review Article BACKGROUND: S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of global cerebral ischemic injury will be dramatically increased. Ischemic brain injury may elevate the level of serum S100B protein and the severity of brain damage. METHODS: This article is a critical and descriptive review on S100B protein in serum after ischemic brain injury. We searched Pubmed database with key words or terms such as “S100B protein”, “cardiac arrest”, “hemorrhagic shock” and “ischemia reperfusion injury” appeared in the last five years. RESULTS: S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of ischemic brain injury will be dramatically increased. Ischemic brain injury elevated the level of serum S100B protein, and the severity of brain damage. CONCLUSION: The level of S100B protein in serum is elevated after ischemic brain injury, but its mechanism is unclear. Second Affiliated Hospital of Zhejiang University School of Medicine 2013 /pmc/articles/PMC4129854/ /pubmed/25215112 http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.001 Text en Copyright: © World Journal of Emergency Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sun, Bao-di
Liu, Hong-mei
Nie, Shi-nan
S100B protein in serum is elevated after global cerebral ischemic injury
title S100B protein in serum is elevated after global cerebral ischemic injury
title_full S100B protein in serum is elevated after global cerebral ischemic injury
title_fullStr S100B protein in serum is elevated after global cerebral ischemic injury
title_full_unstemmed S100B protein in serum is elevated after global cerebral ischemic injury
title_short S100B protein in serum is elevated after global cerebral ischemic injury
title_sort s100b protein in serum is elevated after global cerebral ischemic injury
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129854/
https://www.ncbi.nlm.nih.gov/pubmed/25215112
http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.001
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