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Factors influencing outcomes after cardiopulmonary resuscitation in emergency department

BACKGROUND: The outcome of cardiopulmonary resuscitation (CPR) may depend on a variety of factors related to patient status or resuscitation management. To evaluate the factors influencing the outcome of CPR after cardiac arrest (CA) will be conducive to improve the effectiveness of resuscitation. T...

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Autores principales: Xue, Ji-ke, Leng, Qiao-yun, Gao, Yu-zhi, Chen, Shou-quan, Li, Zhang-ping, Li, Hui-ping, Huang, Wei-jia, Cheng, Jun-yan, Zhang, Jie, He, Ai-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Affiliated Hospital of Zhejiang University School of Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129855/
https://www.ncbi.nlm.nih.gov/pubmed/25215116
http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.005
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author Xue, Ji-ke
Leng, Qiao-yun
Gao, Yu-zhi
Chen, Shou-quan
Li, Zhang-ping
Li, Hui-ping
Huang, Wei-jia
Cheng, Jun-yan
Zhang, Jie
He, Ai-wen
author_facet Xue, Ji-ke
Leng, Qiao-yun
Gao, Yu-zhi
Chen, Shou-quan
Li, Zhang-ping
Li, Hui-ping
Huang, Wei-jia
Cheng, Jun-yan
Zhang, Jie
He, Ai-wen
author_sort Xue, Ji-ke
collection PubMed
description BACKGROUND: The outcome of cardiopulmonary resuscitation (CPR) may depend on a variety of factors related to patient status or resuscitation management. To evaluate the factors influencing the outcome of CPR after cardiac arrest (CA) will be conducive to improve the effectiveness of resuscitation. Therefore, a study was designed to assess these factors in the emergency department (ED) of a city hospital. METHODS: A CPR registry conforming to the Utstein-style template was conducted in the ED of the First Affiliated Hospital of Wenzhou Medical College from January 2005 to December 2011. The outcomes of CPR were compared in various factors groups. The primary outcomes were rated to return of spontaneous circulation (ROSC), 24-hour survival, survival to discharge and discharge with favorable neurological outcomes. Univariate analysis and multivariable logistic regression analysis were performed to evaluate factors associated with survival. RESULTS: A total of 725 patients were analyzed in the study. Of these patients, 187 (25.8%) had ROSC, 100 (13.8%) survived for 24 hours, 48 (6.6%) survived to discharge, and 23 (3.2%) survived to discharge with favorable neurologic outcomes. A logistic regression analysis demonstrated that the independent predictors of ROSC included traumatic etiology, first monitored rhythms, CPR duration, and total adrenaline dose. The independent predictors of 24-hour survival included traumatic etiology, cardiac etiology, first monitored rhythm and CPR duration. Previous status, cardiac etiology, first monitored rhythms and CPR duration were included in independent predictors of survival to discharge and neurologically favorable survival to discharge. CONCLUSIONS: Shockable rhythms, CPR duration ≤15 minutes and total adrenaline dose ≤5 mg were favorable predictors of ROSC, whereas traumatic etiology was unfavorable. Cardiac etiology, shockable rhythms and CPR duration ≤15 minutes were favorable predictors of 24-hour survival, whereas traumatic etiology was unfavorable. Cardiac etiology, shockable rhythms, CPR duration ≤15 minutes were favorable predictors of survival to discharge and neurologically favorable survival to discharge, but previous terminal illness or multiple organ failure (MOF) was unfavorable.
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spelling pubmed-41298552014-09-11 Factors influencing outcomes after cardiopulmonary resuscitation in emergency department Xue, Ji-ke Leng, Qiao-yun Gao, Yu-zhi Chen, Shou-quan Li, Zhang-ping Li, Hui-ping Huang, Wei-jia Cheng, Jun-yan Zhang, Jie He, Ai-wen World J Emerg Med Original Article BACKGROUND: The outcome of cardiopulmonary resuscitation (CPR) may depend on a variety of factors related to patient status or resuscitation management. To evaluate the factors influencing the outcome of CPR after cardiac arrest (CA) will be conducive to improve the effectiveness of resuscitation. Therefore, a study was designed to assess these factors in the emergency department (ED) of a city hospital. METHODS: A CPR registry conforming to the Utstein-style template was conducted in the ED of the First Affiliated Hospital of Wenzhou Medical College from January 2005 to December 2011. The outcomes of CPR were compared in various factors groups. The primary outcomes were rated to return of spontaneous circulation (ROSC), 24-hour survival, survival to discharge and discharge with favorable neurological outcomes. Univariate analysis and multivariable logistic regression analysis were performed to evaluate factors associated with survival. RESULTS: A total of 725 patients were analyzed in the study. Of these patients, 187 (25.8%) had ROSC, 100 (13.8%) survived for 24 hours, 48 (6.6%) survived to discharge, and 23 (3.2%) survived to discharge with favorable neurologic outcomes. A logistic regression analysis demonstrated that the independent predictors of ROSC included traumatic etiology, first monitored rhythms, CPR duration, and total adrenaline dose. The independent predictors of 24-hour survival included traumatic etiology, cardiac etiology, first monitored rhythm and CPR duration. Previous status, cardiac etiology, first monitored rhythms and CPR duration were included in independent predictors of survival to discharge and neurologically favorable survival to discharge. CONCLUSIONS: Shockable rhythms, CPR duration ≤15 minutes and total adrenaline dose ≤5 mg were favorable predictors of ROSC, whereas traumatic etiology was unfavorable. Cardiac etiology, shockable rhythms and CPR duration ≤15 minutes were favorable predictors of 24-hour survival, whereas traumatic etiology was unfavorable. Cardiac etiology, shockable rhythms, CPR duration ≤15 minutes were favorable predictors of survival to discharge and neurologically favorable survival to discharge, but previous terminal illness or multiple organ failure (MOF) was unfavorable. Second Affiliated Hospital of Zhejiang University School of Medicine 2013 /pmc/articles/PMC4129855/ /pubmed/25215116 http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.005 Text en Copyright: © World Journal of Emergency Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Xue, Ji-ke
Leng, Qiao-yun
Gao, Yu-zhi
Chen, Shou-quan
Li, Zhang-ping
Li, Hui-ping
Huang, Wei-jia
Cheng, Jun-yan
Zhang, Jie
He, Ai-wen
Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title_full Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title_fullStr Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title_full_unstemmed Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title_short Factors influencing outcomes after cardiopulmonary resuscitation in emergency department
title_sort factors influencing outcomes after cardiopulmonary resuscitation in emergency department
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129855/
https://www.ncbi.nlm.nih.gov/pubmed/25215116
http://dx.doi.org/10.5847/wjem.j.issn.1920-8642.2013.03.005
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