The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats

In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitu...

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Autores principales: Wang, Yuwei, Feng, Qianjin, Niu, Xin, Liu, Xinshe, Xu, Kaixia, Yang, Xiangzhu, Wang, Huifeng, Li, Qiuju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129929/
https://www.ncbi.nlm.nih.gov/pubmed/25136475
http://dx.doi.org/10.1155/2014/737961
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author Wang, Yuwei
Feng, Qianjin
Niu, Xin
Liu, Xinshe
Xu, Kaixia
Yang, Xiangzhu
Wang, Huifeng
Li, Qiuju
author_facet Wang, Yuwei
Feng, Qianjin
Niu, Xin
Liu, Xinshe
Xu, Kaixia
Yang, Xiangzhu
Wang, Huifeng
Li, Qiuju
author_sort Wang, Yuwei
collection PubMed
description In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III, n = 11). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus.
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spelling pubmed-41299292014-08-18 The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats Wang, Yuwei Feng, Qianjin Niu, Xin Liu, Xinshe Xu, Kaixia Yang, Xiangzhu Wang, Huifeng Li, Qiuju J Anal Methods Chem Research Article In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III, n = 11). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus. Hindawi Publishing Corporation 2014 2014-07-22 /pmc/articles/PMC4129929/ /pubmed/25136475 http://dx.doi.org/10.1155/2014/737961 Text en Copyright © 2014 Yuwei Wang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Yuwei
Feng, Qianjin
Niu, Xin
Liu, Xinshe
Xu, Kaixia
Yang, Xiangzhu
Wang, Huifeng
Li, Qiuju
The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title_full The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title_fullStr The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title_full_unstemmed The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title_short The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
title_sort therapeutic effect of zuogui wan in gestational diabetes mellitus rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129929/
https://www.ncbi.nlm.nih.gov/pubmed/25136475
http://dx.doi.org/10.1155/2014/737961
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