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The Antileukemia Activity of Natural Product HQ17(3) Is Possibly Associated with Downregulation of miR-17-92 Cluster

The compound 10′(Z),13′(E),15′(E)-heptadecatrienylhydroquinone [HQ17(3)] was purified from the sap of the lacquer tree Rhus succedanea. HQ17(3) has cytotoxic effect on cancer cells and can inhibit topoisomerase (topo) IIα activity. We treated various cancer cells with different doses of HQ17(3) and...

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Detalles Bibliográficos
Autores principales:	Liao, Ya-Chun, Lin, Tzu-Heng, Chen, Chih-Ying, Lin, Shwu-Bin, Au, Lo-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130027/ https://www.ncbi.nlm.nih.gov/pubmed/25140305 http://dx.doi.org/10.1155/2014/306718

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