Transepithelial Transport of PAMAM Dendrimers across Isolated Rat Jejunal Mucosae in Ussing Chambers

[Image: see text] Oral delivery remains a challenge for poorly permeable hydrophilic macromolecules. Poly(amido amine) (PAMAM) dendrimers have shown potential for their possible oral delivery. Transepithelial transport of carboxyl-terminated G3.5 and amine-terminated G4 PAMAM dendrimers was assessed...

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Detalles Bibliográficos
Autores principales: Hubbard, Dallin, Ghandehari, Hamidreza, Brayden, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130240/
https://www.ncbi.nlm.nih.gov/pubmed/24992090
http://dx.doi.org/10.1021/bm5004465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130240/
https://www.ncbi.nlm.nih.gov/pubmed/24992090
http://dx.doi.org/10.1021/bm5004465

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