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Effect of Alkyl Length of Peptide–Polymer Amphiphile on Cargo Encapsulation Stability and Pharmacokinetics of 3-Helix Micelles
[Image: see text] 3-Helix micelles have demonstrated excellent in vitro and in vivo stability. Previous studies showed that the unique design of the peptide–polymer conjugate based on protein tertiary structure as the headgroup is the main design factor to achieve high kinetic stability. In this con...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130244/ https://www.ncbi.nlm.nih.gov/pubmed/24988250 http://dx.doi.org/10.1021/bm5005788 |