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Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity

BACKGROUND: Voriconazole is metabolized by cytochrome P450 (CYP) 2C19 and CYP 3A4. Drug-drug interactions and genetic polymorphisms modulate their activities. CASE PRESENTATION: A 35-year old African female patient with resistant HIV and a cerebral mass of unknown origin was treated with voriconazol...

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Detalles Bibliográficos
Autores principales:	Bouatou, Yassine, Samer, Caroline Flora, Ing Lorenzini, Kuntheavy Roseline, Daali, Youssef, Daou, Samira, Fathi, Marc, Rebsamen, Michela, Desmeules, Jules, Calmy, Alexandra, Escher, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130425/ https://www.ncbi.nlm.nih.gov/pubmed/25120580 http://dx.doi.org/10.1186/1742-6405-11-25

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