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Modulation of Platelet Activation and Thrombus Formation Using a Pan-PI3K Inhibitor S14161

The phosphatidylinositol 3–kinase (PI3K) signaling pathway is critical in modulating platelet functions. In the present study, we evaluated the effect of S14161, a recently identified pan-class I PI3K inhibitor, on platelet activation and thrombus formation. Results showed that S14161 inhibited huma...

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Detalles Bibliográficos
Autores principales:	Yi, Wenxiu, Li, Qiang, Shen, Jian, Ren, Lijie, Liu, Xiaohui, Wang, Qi, He, Sudan, Wu, Qingyu, Hu, Hu, Mao, Xinliang, Zhu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130470/ https://www.ncbi.nlm.nih.gov/pubmed/25115838 http://dx.doi.org/10.1371/journal.pone.0102394

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