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Sinupret Activates CFTR and TMEM16A-Dependent Transepithelial Chloride Transport and Improves Indicators of Mucociliary Clearance
INTRODUCTION: We have previously demonstrated that Sinupret, an established treatment prescribed widely in Europe for respiratory ailments including rhinosinusitis, promotes transepithelial chloride (Cl(−)) secretion in vitro and in vivo. The present study was designed to evaluate other indicators o...
Autores principales: | Zhang, Shaoyan, Skinner, Daniel, Hicks, Stephen Bradley, Bevensee, Mark O., Sorscher, Eric J., Lazrak, Ahmed, Matalon, Sadis, McNicholas, Carmel M., Woodworth, Bradford A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130514/ https://www.ncbi.nlm.nih.gov/pubmed/25117505 http://dx.doi.org/10.1371/journal.pone.0104090 |
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