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Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation
Inducing beta-cell mass expansion in diabetic patients with the aim to restore glucose homeostasis is a promising therapeutic strategy. Although several in vitro studies have been carried out to identify modulators of beta-cell mass expansion, restoring endogenous beta-cell mass in vivo has yet to b...
Autores principales: | Tsuji, Naoki, Ninov, Nikolay, Delawary, Mina, Osman, Sahar, Roh, Alex S., Gut, Philipp, Stainier, Didier Y. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130527/ https://www.ncbi.nlm.nih.gov/pubmed/25117518 http://dx.doi.org/10.1371/journal.pone.0104112 |
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