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Second Generation Inactivated Eastern Equine Encephalitis Virus Vaccine Candidates Protect Mice against a Lethal Aerosol Challenge

Currently, there are no FDA-licensed vaccines or therapeutics for eastern equine encephalitis virus (EEEV) for human use. We recently developed several methods to inactivate CVEV1219, a chimeric live-attenuated eastern equine encephalitis virus (EEEV). Dosage and schedule studies were conducted to e...

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Detalles Bibliográficos
Autores principales: Honnold, Shelley P., Bakken, Russell R., Fisher, Diana, Lind, Cathleen M., Cohen, Jeffrey W., Eccleston, Lori T., Spurgers, Kevin B., Maheshwari, Radha K., Glass, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130539/
https://www.ncbi.nlm.nih.gov/pubmed/25116127
http://dx.doi.org/10.1371/journal.pone.0104708