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Depletion of Regulatory T Cells Augments a Vaccine-Induced T Effector Cell Response against the Liver-Stage of Malaria but Fails to Increase Memory

Regulatory T cells (T(reg)) have been shown to restrict vaccine-induced T cell responses in different experimental models. In these studies CD4(+)CD25(+) T(reg) were depleted using monoclonal antibodies against CD25, which might also interfere with CD25 on non-regulatory T cell populations and would...

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Detalles Bibliográficos
Autores principales:	Espinoza Mora, Maria del Rosario, Steeg, Christiane, Tartz, Susanne, Heussler, Volker, Sparwasser, Tim, Link, Andreas, Fleischer, Bernhard, Jacobs, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130546/ https://www.ncbi.nlm.nih.gov/pubmed/25115805 http://dx.doi.org/10.1371/journal.pone.0104627

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