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Artesunate Abolishes Germinal Center B Cells and Inhibits Autoimmune Arthritis

The antimalarial drug artemisinin and its derivatives exhibit potent immunosuppressive activity in several autoimmune disease models, however the mechanisms are not well-understood. This study was designed to investigate the therapeutic effects and the underlying mechanisms of the artemisinin analog...

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Detalles Bibliográficos
Autores principales: Hou, Lifei, Block, Katharine E., Huang, Haochu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130578/
https://www.ncbi.nlm.nih.gov/pubmed/25116436
http://dx.doi.org/10.1371/journal.pone.0104762