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Cholesterol Metabolism Is Altered in Rett Syndrome: A Study on Plasma and Primary Cultured Fibroblasts Derived from Patients

Rett (RTT) syndrome is a severe neurological disorder that affects almost exclusively females. Several detectable mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2) are responsible for the onset of the disease. MeCP2 is a key transcription regulator involved in gene silencing via me...

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Detalles Bibliográficos
Autores principales:	Segatto, Marco, Trapani, Laura, Di Tunno, Ilenia, Sticozzi, Claudia, Valacchi, Giuseppe, Hayek, Joussef, Pallottini, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130597/ https://www.ncbi.nlm.nih.gov/pubmed/25118178 http://dx.doi.org/10.1371/journal.pone.0104834

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