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Aneuploidy in pluripotent stem cells and implications for cancerous transformation

Owing to a unique set of attributes, human pluripotent stem cells (hPSCs) have emerged as a promising cell source for regenerative medicine, disease modeling and drug discovery. Assurance of genetic stability over long term maintenance of hPSCs is pivotal in this endeavor, but hPSCs can adapt to lif...

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Detalles Bibliográficos
Autores principales:	Na, Jie, Baker, Duncan, Zhang, Jing, Andrews, Peter W., Barbaric, Ivana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130921/ https://www.ncbi.nlm.nih.gov/pubmed/24899134 http://dx.doi.org/10.1007/s13238-014-0073-9

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