E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition

BACKGROUND: E-cadherin is an adherens junction protein that forms homophilic intercellular contacts in epithelial cells while also interacting with the intracellular cytoskeletal networks. It has roles including establishment and maintenance of cell polarity, differentiation, migration and signallin...

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Detalles Bibliográficos
Autores principales: Chen, Augustine, Beetham, Henry, Black, Michael A, Priya, Rashmi, Telford, Bryony J, Guest, Joanne, Wiggins, George A R, Godwin, Tanis D, Yap, Alpha S, Guilford, Parry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131020/
https://www.ncbi.nlm.nih.gov/pubmed/25079037
http://dx.doi.org/10.1186/1471-2407-14-552

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