The power comparison of the haplotype-based collapsing tests and the variant-based collapsing tests for detecting rare variants in pedigrees

BACKGROUND: Both common and rare genetic variants have been shown to contribute to the etiology of complex diseases. Recent genome-wide association studies (GWAS) have successfully investigated how common variants contribute to the genetic factors associated with common human diseases. However, unde...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Shugart, Yin Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131059/
https://www.ncbi.nlm.nih.gov/pubmed/25070353
http://dx.doi.org/10.1186/1471-2164-15-632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131059/
https://www.ncbi.nlm.nih.gov/pubmed/25070353
http://dx.doi.org/10.1186/1471-2164-15-632

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