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IL-17F gene polymorphism is associated with susceptibility to acute myeloid leukemia

PURPOSE: Recent studies have suggested that Th17 cells may play a role in the pathogenesis of acute myeloid leukemia (AML). This subset of CD4+ cells is characterized by interleukin (IL)-17A and IL-17F production, which share strong homology, and surface expression of the IL-23 receptor (IL-23R). Th...

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Detalles Bibliográficos
Autores principales: Wróbel, Tomasz, Gębura, Katarzyna, Wysoczańska, Barbara, Jaźwiec, Bożena, Dobrzyńska, Olga, Mazur, Grzegorz, Kuliczkowski, Kazimierz, Bogunia-Kubik, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131129/
https://www.ncbi.nlm.nih.gov/pubmed/24793548
http://dx.doi.org/10.1007/s00432-014-1674-7