Cargando…

Microglia as a critical player in both developmental and late-life CNS pathologies

Microglia, the tissue-resident macrophages of the brain, are attracting increasing attention as key players in brain homeostasis from development through aging. Recent works have highlighted new and unexpected roles for these once-enigmatic cells in both healthy central nervous system function and i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Derecki, Noël C., Katzmarski, Natalie, Kipnis, Jonathan, Meyer-Luehmann, Melanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131160/ https://www.ncbi.nlm.nih.gov/pubmed/25056803 http://dx.doi.org/10.1007/s00401-014-1321-z

Ejemplares similares

Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures
por: Hellwig, Sabine, et al.
Publicado: (2015)

Wild type microglia arrest pathology in a mouse model of Rett syndrome
por: Derecki, Noël C., et al.
Publicado: (2012)

Immune cells and CNS physiology: Microglia and beyond
por: Norris, Geoffrey T., et al.
Publicado: (2019)

Seed‐induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease
por: Ziegler‐Waldkirch, Stephanie, et al.
Publicado: (2017)

Distinct Aβ pathology in the olfactory bulb and olfactory deficits in a mouse model of Aβ and α‐syn co‐pathology
por: Friesen, Marina, et al.
Publicado: (2021)

Dynamics of the Meningeal CD4(+) T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice
por: Radjavi, Ali, et al.
Publicado: (2013)

Aβ oligomers trigger and accelerate Aβ seeding
por: Katzmarski, Natalie, et al.
Publicado: (2019)

Aβ Seeding as a Tool to Study Cerebral Amyloidosis and Associated Pathology
por: Friesen, Marina, et al.
Publicado: (2019)

Role of Microglia in CNS Autoimmunity
por: Goldmann, Tobias, et al.
Publicado: (2013)

Microglia morphophysiological diversity and its implications for the CNS
por: Vidal-Itriago, Andrés, et al.
Publicado: (2022)

Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury
por: Norris, Geoffrey T., et al.
Publicado: (2018)

miRNAs in Microglia: Important Players in Multiple Sclerosis Pathology
por: Walsh, Alexander D., et al.
Publicado: (2021)

Detection of Synaptic Proteins in Microglia by Flow Cytometry
por: Brioschi, Simone, et al.
Publicado: (2020)

Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
por: Traiffort, Elisabeth, et al.
Publicado: (2020)

Corrigendum to miRNAs in Microglia: Important Players in Multiple Sclerosis Pathology
Publicado: (2022)

Microglia exit the CNS in spinal root avulsion
por: Green, Lauren A., et al.
Publicado: (2019)

Microglia: Agents of the CNS Pro-Inflammatory Response
por: Rodríguez-Gómez, José A., et al.
Publicado: (2020)

Comparative Review of Microglia and Monocytes in CNS Phagocytosis
por: Andoh, Megumi, et al.
Publicado: (2021)

Microglia – the brain’s busy bees
por: Cronk, James C., et al.
Publicado: (2013)

Regulation of learning and memory by meningeal immunity: a key role for IL-4
por: Derecki, Noël C., et al.
Publicado: (2010)

Sphingolipids as critical players in retinal physiology and pathology
por: Simon, M. Victoria, et al.
Publicado: (2021)

Microglia and CNS Interleukin-1: Beyond Immunological Concepts
por: Liu, Xiaoyu, et al.
Publicado: (2018)

The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer
por: Yin, Jie, et al.
Publicado: (2017)

Exploring the VISTA of microglia: immune checkpoints in CNS inflammation
por: Borggrewe, Malte, et al.
Publicado: (2020)

Editorial: Modulation of microglia reactivity and plasticity in CNS injury
por: He, Zhenyan, et al.
Publicado: (2023)

Gut Microbiota to Microglia: Microbiome Influences Neurodevelopment in the CNS
por: Bettag, Jeffery, et al.
Publicado: (2023)

Aberrant Synaptic Pruning in CNS Diseases: A Critical Player in HIV-Associated Neurological Dysfunction?
por: Watson, Zachary, et al.
Publicado: (2022)

Transplanting Microglia for Treating CNS Injuries and Neurological Diseases and Disorders, and Prospects for Generating Exogenic Microglia
por: Var, Susanna R., et al.
Publicado: (2023)

Extracellular Vesicles in CNS Developmental Disorders
por: Gomes, Ana Rita, et al.
Publicado: (2020)

Impact of Aging in Microglia-Mediated D-Serine Balance in the CNS
por: Beltrán-Castillo, Sebastián, et al.
Publicado: (2018)

LRP1 expression in microglia is protective during CNS autoimmunity
por: Chuang, Tzu-Ying, et al.
Publicado: (2016)

Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
por: Spiteri, Alanna G., et al.
Publicado: (2021)

Mertk-expressing microglia influence oligodendrogenesis and myelin modelling in the CNS
por: Nguyen, Linda T., et al.
Publicado: (2023)

A Peephole into the Brain: Neuropathological Features of Alzheimer’s Disease Revealed by in vivo Two-Photon Imaging
por: Liebscher, Sabine, et al.
Publicado: (2012)

The node of Ranvier in CNS pathology
por: Arancibia-Carcamo, I. Lorena, et al.
Publicado: (2014)

JNK Pathway in CNS Pathologies
por: de los Reyes Corrales, Teresa, et al.
Publicado: (2021)

Microglia: An Active Player in the Regulation of Synaptic Activity
por: Ji, Kyungmin, et al.
Publicado: (2013)

Microglia: Key Players in Retinal Ageing and Neurodegeneration
por: Guo, Li, et al.
Publicado: (2022)

Pathology-induced NG2 proteoglycan expression in microglia
por: Meyer, Erika, et al.
Publicado: (2022)

The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease
por: Ziegler-Waldkirch, Stephanie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bfdiqg49r2re7rnf17gmcl952e