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Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

The evolution from microarrays to transcriptome deep-sequencing (RNA-seq) and from RNA interference to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and Transcription Activator-Like Effector Nucleases (TALENs) has provided a new experimental partnership for...

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Detalles Bibliográficos
Autores principales:	Rathe, Susan K., Moriarity, Branden S., Stoltenberg, Christopher B., Kurata, Morito, Aumann, Natalie K., Rahrmann, Eric P., Bailey, Natashay J., Melrose, Ellen G., Beckmann, Dominic A., Liska, Chase R., Largaespada, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131221/ https://www.ncbi.nlm.nih.gov/pubmed/25116387 http://dx.doi.org/10.1038/srep06048

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