Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana

In this study, 23 oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. The NF-κB inhibitory activity of the isolated compounds was measured in TNFα-treated HepG2 cells using a luciferase reporter system. Compounds 19–23 inhibited TNFα-stimulat...

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Detalles Bibliográficos
Autores principales: Li, Wei, Yan, Xi Tao, Sun, Ya Nan, Ngan, Thi Thanh, Shim, Sang Hee, Kim, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131524/
https://www.ncbi.nlm.nih.gov/pubmed/25143813
http://dx.doi.org/10.4062/biomolther.2014.047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131524/
https://www.ncbi.nlm.nih.gov/pubmed/25143813
http://dx.doi.org/10.4062/biomolther.2014.047

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