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Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana
In this study, 23 oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. The NF-κB inhibitory activity of the isolated compounds was measured in TNFα-treated HepG2 cells using a luciferase reporter system. Compounds 19–23 inhibited TNFα-stimulat...
Autores principales: | Li, Wei, Yan, Xi Tao, Sun, Ya Nan, Ngan, Thi Thanh, Shim, Sang Hee, Kim, Young Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131524/ https://www.ncbi.nlm.nih.gov/pubmed/25143813 http://dx.doi.org/10.4062/biomolther.2014.047 |
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