New benzene derivatives from cultures of ascomycete Daldinia concentrica

Three new benzene derivatives, named daldins A-C (1–3), together with a known analogue, 2-hydroxymethyl-3-(1-hydroxypropyl) phenol (4) have been isolated from cultures of ascomycete Daldinia concentrica. The structures of 1–4 with absolute configuration were established by means of spectroscopic methods and X-ray diffraction. All compounds showed no significant inhibition on five human cancer cell lines with IC(50) values > 40 μmol. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-013-0048-1 and is accessible for authorized users.