Chemical constituents from Munronia sinica and their bioactivities

Two new minor constituents, musinisins A (1) and B (2), together with five known compounds (3–7), were isolated from the aerial parts of Munronia sinica. Their structures were established by means of spectroscopic methods and the absolute stereochemistry of 1 was determined by single crystal X-ray e...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Li, He, Qiu-Xia, Zhang, Feng-Lei, Zhao, Yan-Li, Liu, Ke-Chun, Jiang, Si-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131585/
http://dx.doi.org/10.1007/s13659-012-0001-8
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author Li, Xiao-Li
He, Qiu-Xia
Zhang, Feng-Lei
Zhao, Yan-Li
Liu, Ke-Chun
Jiang, Si-Ping
author_facet Li, Xiao-Li
He, Qiu-Xia
Zhang, Feng-Lei
Zhao, Yan-Li
Liu, Ke-Chun
Jiang, Si-Ping
author_sort Li, Xiao-Li
collection PubMed
description Two new minor constituents, musinisins A (1) and B (2), together with five known compounds (3–7), were isolated from the aerial parts of Munronia sinica. Their structures were established by means of spectroscopic methods and the absolute stereochemistry of 1 was determined by single crystal X-ray experiment. Compound 4 showed antiangiogenic activity evaluated by a zebrafish model and apoptosis-inducing effect on A549 lung cancer cells. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0001-8 and is accessible for authorized users.
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spelling pubmed-41315852014-08-20 Chemical constituents from Munronia sinica and their bioactivities Li, Xiao-Li He, Qiu-Xia Zhang, Feng-Lei Zhao, Yan-Li Liu, Ke-Chun Jiang, Si-Ping Nat Prod Bioprospect Regular Article Two new minor constituents, musinisins A (1) and B (2), together with five known compounds (3–7), were isolated from the aerial parts of Munronia sinica. Their structures were established by means of spectroscopic methods and the absolute stereochemistry of 1 was determined by single crystal X-ray experiment. Compound 4 showed antiangiogenic activity evaluated by a zebrafish model and apoptosis-inducing effect on A549 lung cancer cells. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0001-8 and is accessible for authorized users. Springer Berlin Heidelberg 2012-03-22 /pmc/articles/PMC4131585/ http://dx.doi.org/10.1007/s13659-012-0001-8 Text en © The Author(s) 2012
spellingShingle Regular Article
Li, Xiao-Li
He, Qiu-Xia
Zhang, Feng-Lei
Zhao, Yan-Li
Liu, Ke-Chun
Jiang, Si-Ping
Chemical constituents from Munronia sinica and their bioactivities
title Chemical constituents from Munronia sinica and their bioactivities
title_full Chemical constituents from Munronia sinica and their bioactivities
title_fullStr Chemical constituents from Munronia sinica and their bioactivities
title_full_unstemmed Chemical constituents from Munronia sinica and their bioactivities
title_short Chemical constituents from Munronia sinica and their bioactivities
title_sort chemical constituents from munronia sinica and their bioactivities
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131585/
http://dx.doi.org/10.1007/s13659-012-0001-8
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