Four new indole alkaloids from Plantago asiatica

Four new indole alkaloids, plasiaticines A-D (1–4), together with two known ones, were isolated from the seeds of Plantago asiatica. The structures of the new compounds were elucidated on the basis of comprehensive analysis of spectroscopic data. All compounds were tested for their cytotoxic activit...

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Detalles Bibliográficos
Autores principales: Gao, Zhong-Hua, Kong, Ling-Mei, Zou, Xi-Sheng, Shi, Yi-Ming, Shang, Shan-Zhai, Luo, Huai-Rong, Liang, Cheng-Qin, Li, Xiao-Nian, Li, Yan, Du, Xue, Xiao, Wei-Lie, Sun, Han-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131610/
http://dx.doi.org/10.1007/s13659-012-0082-4
Descripción
Sumario:Four new indole alkaloids, plasiaticines A-D (1–4), together with two known ones, were isolated from the seeds of Plantago asiatica. The structures of the new compounds were elucidated on the basis of comprehensive analysis of spectroscopic data. All compounds were tested for their cytotoxic activity, and all compounds except 4 were tested for their acetylcholinesterase (AChE) inhibitory activities. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0082-4 and is accessible for authorized users.

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