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Epigenetic modifier-induced biosynthesis of novel fusaric acid derivatives in endophytic fungi from Datura stramonium L.

ABSTRACT: The treatment of fungi with DNA methyltransferase (DNMT) and/or histone deacetylase (HDAC) inhibitors is a promising way to activate secondary metabolite biosynthetic pathways that are dormant under normal conditions. In this study, we included an HDAC inhibitor, suberoylanilide hydroxamic...

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Detalles Bibliográficos
Autores principales: Chen, Han-Jing, Awakawa, Takayoshi, Sun, Jie-Yin, Wakimoto, Toshiyuki, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131616/
http://dx.doi.org/10.1007/s13659-013-0010-2