Five new mexicanolide type limonoids from Heynea trijuga

Five new mexicanolide-type limonoids, heytrijunolides A–E (1–5) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compound 3 showed weak cytotoxicity against HL-60, SMMC-7721 and A-549...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Kong, Ling-Mei, Li, Shi-Fei, Li, Yan, Zhang, Yu, He, Hong-Ping, Hao, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131624/
http://dx.doi.org/10.1007/s13659-012-0040-1
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author Yang, Wei
Kong, Ling-Mei
Li, Shi-Fei
Li, Yan
Zhang, Yu
He, Hong-Ping
Hao, Xiao-Jiang
author_facet Yang, Wei
Kong, Ling-Mei
Li, Shi-Fei
Li, Yan
Zhang, Yu
He, Hong-Ping
Hao, Xiao-Jiang
author_sort Yang, Wei
collection PubMed
description Five new mexicanolide-type limonoids, heytrijunolides A–E (1–5) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compound 3 showed weak cytotoxicity against HL-60, SMMC-7721 and A-549 human tumor cell lines with the IC(50) values of 21.88, 20.66 and 12.70 µM, respectively. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0040-1 and is accessible for authorized users.
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spelling pubmed-41316242014-08-20 Five new mexicanolide type limonoids from Heynea trijuga Yang, Wei Kong, Ling-Mei Li, Shi-Fei Li, Yan Zhang, Yu He, Hong-Ping Hao, Xiao-Jiang Nat Prod Bioprospect Regular Article Five new mexicanolide-type limonoids, heytrijunolides A–E (1–5) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compound 3 showed weak cytotoxicity against HL-60, SMMC-7721 and A-549 human tumor cell lines with the IC(50) values of 21.88, 20.66 and 12.70 µM, respectively. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0040-1 and is accessible for authorized users. Springer Berlin Heidelberg 2012-06-11 /pmc/articles/PMC4131624/ http://dx.doi.org/10.1007/s13659-012-0040-1 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Regular Article
Yang, Wei
Kong, Ling-Mei
Li, Shi-Fei
Li, Yan
Zhang, Yu
He, Hong-Ping
Hao, Xiao-Jiang
Five new mexicanolide type limonoids from Heynea trijuga
title Five new mexicanolide type limonoids from Heynea trijuga
title_full Five new mexicanolide type limonoids from Heynea trijuga
title_fullStr Five new mexicanolide type limonoids from Heynea trijuga
title_full_unstemmed Five new mexicanolide type limonoids from Heynea trijuga
title_short Five new mexicanolide type limonoids from Heynea trijuga
title_sort five new mexicanolide type limonoids from heynea trijuga
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131624/
http://dx.doi.org/10.1007/s13659-012-0040-1
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