Three new triterpenoids from Rubia schumanniana

Three new triterpenoids, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyl-12-en-28-oic-acid (1), 3β-hydroxy-olean-30-p-Ehydroxycinnamoyl-12-en-28-oic-acid (2) and 3β,6α-dihydroxy-urs-14-en-12-one (3), together with seven known triterpenoids, were isolated from the roots of Rubia schumanniana. Their structures...

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Detalles Bibliográficos
Autores principales: Kuang, Bin, Han, Jing, Zeng, Guang-Zhi, Chen, Xiao-Qiang, He, Wen-Jun, Tan, Ning-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131627/
http://dx.doi.org/10.1007/s13659-012-0038-8
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author Kuang, Bin
Han, Jing
Zeng, Guang-Zhi
Chen, Xiao-Qiang
He, Wen-Jun
Tan, Ning-Hua
author_facet Kuang, Bin
Han, Jing
Zeng, Guang-Zhi
Chen, Xiao-Qiang
He, Wen-Jun
Tan, Ning-Hua
author_sort Kuang, Bin
collection PubMed
description Three new triterpenoids, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyl-12-en-28-oic-acid (1), 3β-hydroxy-olean-30-p-Ehydroxycinnamoyl-12-en-28-oic-acid (2) and 3β,6α-dihydroxy-urs-14-en-12-one (3), together with seven known triterpenoids, were isolated from the roots of Rubia schumanniana. Their structures were established by means of spectroscopic analysis. All compounds were evaluated for cytotoxic activity, and compounds 2–6 showed cytotoxicity with the IC50 values of 10.75∼18.87 µg/mL. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0038-8 and is accessible for authorized users.
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spelling pubmed-41316272014-08-20 Three new triterpenoids from Rubia schumanniana Kuang, Bin Han, Jing Zeng, Guang-Zhi Chen, Xiao-Qiang He, Wen-Jun Tan, Ning-Hua Nat Prod Bioprospect Regular Article Three new triterpenoids, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyl-12-en-28-oic-acid (1), 3β-hydroxy-olean-30-p-Ehydroxycinnamoyl-12-en-28-oic-acid (2) and 3β,6α-dihydroxy-urs-14-en-12-one (3), together with seven known triterpenoids, were isolated from the roots of Rubia schumanniana. Their structures were established by means of spectroscopic analysis. All compounds were evaluated for cytotoxic activity, and compounds 2–6 showed cytotoxicity with the IC50 values of 10.75∼18.87 µg/mL. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-012-0038-8 and is accessible for authorized users. Springer Berlin Heidelberg 2012-07-12 /pmc/articles/PMC4131627/ http://dx.doi.org/10.1007/s13659-012-0038-8 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Regular Article
Kuang, Bin
Han, Jing
Zeng, Guang-Zhi
Chen, Xiao-Qiang
He, Wen-Jun
Tan, Ning-Hua
Three new triterpenoids from Rubia schumanniana
title Three new triterpenoids from Rubia schumanniana
title_full Three new triterpenoids from Rubia schumanniana
title_fullStr Three new triterpenoids from Rubia schumanniana
title_full_unstemmed Three new triterpenoids from Rubia schumanniana
title_short Three new triterpenoids from Rubia schumanniana
title_sort three new triterpenoids from rubia schumanniana
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131627/
http://dx.doi.org/10.1007/s13659-012-0038-8
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