Norsesquiterpenoids from the leaves of Croton tiglium

Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-cryst...

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Detalles Bibliográficos
Autores principales: Bu, Wei, Shi, Yan-Ni, Yan, Yong-Ming, Lu, Qing, Liu, Guang-Ming, Li, Yan, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131640/
http://dx.doi.org/10.1007/s13659-011-0035-3
Descripción
Sumario:Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0035-3 and is accessible for authorized users.

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