Norsesquiterpenoids from the leaves of Croton tiglium

Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-cryst...

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Detalles Bibliográficos
Autores principales: Bu, Wei, Shi, Yan-Ni, Yan, Yong-Ming, Lu, Qing, Liu, Guang-Ming, Li, Yan, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131640/
http://dx.doi.org/10.1007/s13659-011-0035-3
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author Bu, Wei
Shi, Yan-Ni
Yan, Yong-Ming
Lu, Qing
Liu, Guang-Ming
Li, Yan
Cheng, Yong-Xian
author_facet Bu, Wei
Shi, Yan-Ni
Yan, Yong-Ming
Lu, Qing
Liu, Guang-Ming
Li, Yan
Cheng, Yong-Xian
author_sort Bu, Wei
collection PubMed
description Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0035-3 and is accessible for authorized users.
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spelling pubmed-41316402014-08-20 Norsesquiterpenoids from the leaves of Croton tiglium Bu, Wei Shi, Yan-Ni Yan, Yong-Ming Lu, Qing Liu, Guang-Ming Li, Yan Cheng, Yong-Xian Nat Prod Bioprospect Short Communication Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0035-3 and is accessible for authorized users. Springer Berlin Heidelberg 2012-01-02 /pmc/articles/PMC4131640/ http://dx.doi.org/10.1007/s13659-011-0035-3 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Short Communication
Bu, Wei
Shi, Yan-Ni
Yan, Yong-Ming
Lu, Qing
Liu, Guang-Ming
Li, Yan
Cheng, Yong-Xian
Norsesquiterpenoids from the leaves of Croton tiglium
title Norsesquiterpenoids from the leaves of Croton tiglium
title_full Norsesquiterpenoids from the leaves of Croton tiglium
title_fullStr Norsesquiterpenoids from the leaves of Croton tiglium
title_full_unstemmed Norsesquiterpenoids from the leaves of Croton tiglium
title_short Norsesquiterpenoids from the leaves of Croton tiglium
title_sort norsesquiterpenoids from the leaves of croton tiglium
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131640/
http://dx.doi.org/10.1007/s13659-011-0035-3
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