Dammarane-type saponins from steamed leaves of Panax Notoginseng

Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt(1)-SFt(4) (1–4) were isolated from the steamed leaves of Panax notoginseng (Burk.) F. H. Chen (Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses an...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Lv, Jun-Jiang, Xu, Min, Wang, Dong, Zhu, Hong-Tao, Yang, Chong-Ren, Zhang, Ying-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2011
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131641/
http://dx.doi.org/10.1007/s13659-011-0036-2
Descripción
Sumario:Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt(1)-SFt(4) (1–4) were isolated from the steamed leaves of Panax notoginseng (Burk.) F. H. Chen (Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses and acidic hydrolysis. The known ginsenosides Rk2 and Rh3 were obtained from P. notoginseng for the first time. All of these new saponins showed no in vitro cytotoxicity against five human cancer cell lines (HL-60, SMMC-7712, A-549, MCF-7, and SW480). [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0036-2 and is accessible for authorized users.

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