Three new indole alkaloids from Rauvolfia yunnanensis

One rare tetracyclic macroline-type indole alkaloid, named rauvoyunine A (1), and two new picraline-type alkaloids rauvoyunines B and C (2 and 3) were isolated from the aerial parts of Rauvolfia yunnanensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Wang, Fei, Zhou, Dong-Sheng, Li, Yan, Liu, Ji-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2011
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131643/
http://dx.doi.org/10.1007/s13659-011-0023-7
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author Gao, Yuan
Wang, Fei
Zhou, Dong-Sheng
Li, Yan
Liu, Ji-Kai
author_facet Gao, Yuan
Wang, Fei
Zhou, Dong-Sheng
Li, Yan
Liu, Ji-Kai
author_sort Gao, Yuan
collection PubMed
description One rare tetracyclic macroline-type indole alkaloid, named rauvoyunine A (1), and two new picraline-type alkaloids rauvoyunines B and C (2 and 3) were isolated from the aerial parts of Rauvolfia yunnanensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0023-7 and is accessible for authorized users.
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spelling pubmed-41316432014-08-20 Three new indole alkaloids from Rauvolfia yunnanensis Gao, Yuan Wang, Fei Zhou, Dong-Sheng Li, Yan Liu, Ji-Kai Nat Prod Bioprospect Regular Article One rare tetracyclic macroline-type indole alkaloid, named rauvoyunine A (1), and two new picraline-type alkaloids rauvoyunines B and C (2 and 3) were isolated from the aerial parts of Rauvolfia yunnanensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-011-0023-7 and is accessible for authorized users. Springer Berlin Heidelberg 2011-12-01 /pmc/articles/PMC4131643/ http://dx.doi.org/10.1007/s13659-011-0023-7 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Regular Article
Gao, Yuan
Wang, Fei
Zhou, Dong-Sheng
Li, Yan
Liu, Ji-Kai
Three new indole alkaloids from Rauvolfia yunnanensis
title Three new indole alkaloids from Rauvolfia yunnanensis
title_full Three new indole alkaloids from Rauvolfia yunnanensis
title_fullStr Three new indole alkaloids from Rauvolfia yunnanensis
title_full_unstemmed Three new indole alkaloids from Rauvolfia yunnanensis
title_short Three new indole alkaloids from Rauvolfia yunnanensis
title_sort three new indole alkaloids from rauvolfia yunnanensis
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131643/
http://dx.doi.org/10.1007/s13659-011-0023-7
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