Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone

A concise synthetic route leading to highly functional erythrina alkaloid skeletons has been developed. The key process is an oxidative carbon-carbon coupling followed by a conjugated addition. Based on this new strategy, a formal synthesis of demethoxyerythratidinone was completed in only 6 steps f...

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Detalles Bibliográficos
Autores principales: Pan, Zhi-Qiang, Liang, Ji-Xuan, Chen, Jing-Bo, Yang, Xiao-Dong, Zhang, Hong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2011
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131647/
http://dx.doi.org/10.1007/s13659-011-0045-1
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author Pan, Zhi-Qiang
Liang, Ji-Xuan
Chen, Jing-Bo
Yang, Xiao-Dong
Zhang, Hong-Bin
author_facet Pan, Zhi-Qiang
Liang, Ji-Xuan
Chen, Jing-Bo
Yang, Xiao-Dong
Zhang, Hong-Bin
author_sort Pan, Zhi-Qiang
collection PubMed
description A concise synthetic route leading to highly functional erythrina alkaloid skeletons has been developed. The key process is an oxidative carbon-carbon coupling followed by a conjugated addition. Based on this new strategy, a formal synthesis of demethoxyerythratidinone was completed in only 6 steps from 4-aminophenol. [Image: see text]
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spelling pubmed-41316472014-08-20 Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone Pan, Zhi-Qiang Liang, Ji-Xuan Chen, Jing-Bo Yang, Xiao-Dong Zhang, Hong-Bin Nat Prod Bioprospect Regular Article A concise synthetic route leading to highly functional erythrina alkaloid skeletons has been developed. The key process is an oxidative carbon-carbon coupling followed by a conjugated addition. Based on this new strategy, a formal synthesis of demethoxyerythratidinone was completed in only 6 steps from 4-aminophenol. [Image: see text] Springer Berlin Heidelberg 2011-12-23 /pmc/articles/PMC4131647/ http://dx.doi.org/10.1007/s13659-011-0045-1 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Regular Article
Pan, Zhi-Qiang
Liang, Ji-Xuan
Chen, Jing-Bo
Yang, Xiao-Dong
Zhang, Hong-Bin
Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title_full Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title_fullStr Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title_full_unstemmed Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title_short Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
title_sort oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131647/
http://dx.doi.org/10.1007/s13659-011-0045-1
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