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Triterpenoid alkaloid derivatives from Buxus rugulosa

Four new triterpenoid alkaloid derivatives, buxrugulines A–D (1–4), together with four known ones (5–8), were isolated from the leaves and stems of Buxus rugulosa. The structures of compounds 1–4 were elucidated by NMR and MS spectroscopic analysis. All compounds were assayed for their cytotoxicitie...

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Detalles Bibliográficos
Autores principales: Yan, Yu-Xin, Zhou, Lin, Sun, Yun, Chen, Jian-Chao, Su, Jia, Li, Yan, Qiu, Ming-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131653/
http://dx.doi.org/10.1007/s13659-011-0010-z
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author Yan, Yu-Xin
Zhou, Lin
Sun, Yun
Chen, Jian-Chao
Su, Jia
Li, Yan
Qiu, Ming-Hua
author_facet Yan, Yu-Xin
Zhou, Lin
Sun, Yun
Chen, Jian-Chao
Su, Jia
Li, Yan
Qiu, Ming-Hua
author_sort Yan, Yu-Xin
collection PubMed
description Four new triterpenoid alkaloid derivatives, buxrugulines A–D (1–4), together with four known ones (5–8), were isolated from the leaves and stems of Buxus rugulosa. The structures of compounds 1–4 were elucidated by NMR and MS spectroscopic analysis. All compounds were assayed for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, and SW480 cells lines. [Image: see text]
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spelling pubmed-41316532014-08-20 Triterpenoid alkaloid derivatives from Buxus rugulosa Yan, Yu-Xin Zhou, Lin Sun, Yun Chen, Jian-Chao Su, Jia Li, Yan Qiu, Ming-Hua Nat Prod Bioprospect Regular Article Four new triterpenoid alkaloid derivatives, buxrugulines A–D (1–4), together with four known ones (5–8), were isolated from the leaves and stems of Buxus rugulosa. The structures of compounds 1–4 were elucidated by NMR and MS spectroscopic analysis. All compounds were assayed for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, and SW480 cells lines. [Image: see text] Springer Berlin Heidelberg 2011-09-21 /pmc/articles/PMC4131653/ http://dx.doi.org/10.1007/s13659-011-0010-z Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Regular Article
Yan, Yu-Xin
Zhou, Lin
Sun, Yun
Chen, Jian-Chao
Su, Jia
Li, Yan
Qiu, Ming-Hua
Triterpenoid alkaloid derivatives from Buxus rugulosa
title Triterpenoid alkaloid derivatives from Buxus rugulosa
title_full Triterpenoid alkaloid derivatives from Buxus rugulosa
title_fullStr Triterpenoid alkaloid derivatives from Buxus rugulosa
title_full_unstemmed Triterpenoid alkaloid derivatives from Buxus rugulosa
title_short Triterpenoid alkaloid derivatives from Buxus rugulosa
title_sort triterpenoid alkaloid derivatives from buxus rugulosa
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131653/
http://dx.doi.org/10.1007/s13659-011-0010-z
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