Four new lignans from the leaves and stems of Schisandra propinqua var. sinensis

Four new tetrahydrofuran lignans, schpropinrins A-D (1–4), together with five known ones, were isolated from the leaves and stems of Schisandra propinqua var. sinensis. Their structures, including absolute configurations, were characterized by means of spectroscopic analysis and ECD calculation. Com...

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Detalles Bibliográficos
Autores principales: Shang, Shan-Zhai, Han, Ying-Shan, Shi, Yi-Ming, Du, Xue, Liang, Cheng-Qin, Wainberg, Mark A., Gao, Zhong-Hua, Xiao, Wei-Lie, Sun, Han-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131657/
http://dx.doi.org/10.1007/s13659-013-0017-8
Descripción
Sumario:Four new tetrahydrofuran lignans, schpropinrins A-D (1–4), together with five known ones, were isolated from the leaves and stems of Schisandra propinqua var. sinensis. Their structures, including absolute configurations, were characterized by means of spectroscopic analysis and ECD calculation. Compounds 1–4 featured a ketal or hemiketal substructure at C-7 and all of the isolates were tested for their anti-HIV integrase activity. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s13659-013-0017-8 and is accessible for authorized users.

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