Persistent Release of IL-1s from Skin Is Associated with Systemic Cardio-Vascular Disease, Emaciation and Systemic Amyloidosis: The Potential of Anti-IL-1 Therapy for Systemic Inflammatory Diseases

The skin is an immune organ that contains innate and acquired immune systems and thus is able to respond to exogenous stimuli producing large amount of proinflammatory cytokines including IL-1 and IL-1 family members. The role of the epidermal IL-1 is not limited to initiation of local inflammatory...

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Detalles Bibliográficos
Autores principales: Yamanaka, Keiichi, Nakanishi, Takehisa, Saito, Hiromitsu, Maruyama, Junko, Isoda, Kenichi, Yokochi, Ayumu, Imanaka-Yoshida, Kyoko, Tsuda, Kenshiro, Kakeda, Masato, Okamoto, Ryuji, Fujita, Satoshi, Iwakura, Yoichiro, Suzuki, Noboru, Ito, Masaaki, Maruyama, Kazuo, Gabazza, Esteban C., Yoshida, Toshimichi, Shimaoka, Motomu, Mizutani, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131904/
https://www.ncbi.nlm.nih.gov/pubmed/25119884
http://dx.doi.org/10.1371/journal.pone.0104479

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