Cargando…

Tumour Cells Expressing Single VEGF Isoforms Display Distinct Growth, Survival and Migration Characteristics

Vascular endothelial growth factor-A (VEGF) is produced by most cancer cells as multiple isoforms, which display distinct biological activities. VEGF plays an undisputed role in tumour growth, vascularisation and metastasis; nevertheless the functions of individual isoforms in these processes remain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kanthou, Chryso, Dachs, Gabi U., Lefley, Diane V., Steele, Andrew J., Coralli-Foxon, Claudia, Harris, Sheila, Greco, Olga, Dos Santos, Sofia A., Reyes-Aldasoro, Constantino C., English, William R., Tozer, Gillian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131915/ https://www.ncbi.nlm.nih.gov/pubmed/25119572 http://dx.doi.org/10.1371/journal.pone.0104015

Ejemplares similares

Do Anti-Angiogenic VEGF (VEGFxxxb) Isoforms Exist? A Cautionary Tale
por: Harris, Sheila, et al.
Publicado: (2012)

Anti-vascular agent Combretastatin A-4-P modulates Hypoxia Inducible Factor-1 and gene expression
por: Dachs, Gabi U, et al.
Publicado: (2006)

The protective role of sphingosine-1-phosphate against the action of the vascular disrupting agent combretastatin A-4 3-O-phosphate
por: Shepherd, Joanna, et al.
Publicado: (2017)

An in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate
por: Williams, L J, et al.
Publicado: (2014)

Gene delivery to hypoxic cells in vitro
por: Dachs, G U, et al.
Publicado: (2000)

Wearable Insulin Biosensors for Diabetes Management: Advances and Challenges
por: Psoma, Sotiria D., et al.
Publicado: (2023)

The influence of hypoxia and energy depletion on the response of endothelial cells to the vascular disrupting agent combretastatin A-4-phosphate
por: Holmes, Toby, et al.
Publicado: (2020)

Direct visualization of electroporation-assisted in vivo gene delivery to tumors using intravital microscopy – spatial and time dependent distribution
por: Cemazar, Maja, et al.
Publicado: (2004)

Modelling the Tumour Microenvironment, but What Exactly Do We Mean by “Model”?
por: Reyes-Aldasoro, Constantino Carlos
Publicado: (2023)

The proportion of cancer-related entries in PubMed has increased considerably; is cancer truly “The Emperor of All Maladies”?
por: Reyes-Aldasoro, Constantino Carlos
Publicado: (2017)

MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics
por: Di Benedetto, Melanie, et al.
Publicado: (2015)

VEGF(121)b and VEGF(165)b are weakly angiogenic isoforms of VEGF-A
por: Catena, Raúl, et al.
Publicado: (2010)

Antiangiogenic VEGF Isoform in Inflammatory Myopathies
por: Volpi, Nila, et al.
Publicado: (2013)

Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma
por: Pritchard-Jones, R O, et al.
Publicado: (2007)

The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice
por: Rennel, E S, et al.
Publicado: (2008)

Comparison of Convolutional Neural Networks and Transformers for the Classification of Images of COVID-19, Pneumonia and Healthy Individuals as Observed with Computed Tomography
por: Ascencio-Cabral, Azucena, et al.
Publicado: (2022)

VEGF in the lung: a role for novel isoforms
por: Varet, Julia, et al.
Publicado: (2010)

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo
por: Rennel, E S, et al.
Publicado: (2009)

Experimental Assessment of Color Deconvolution and Color Normalization for Automated Classification of Histology Images Stained with Hematoxylin and Eosin
por: Bianconi, Francesco, et al.
Publicado: (2020)

Volumetric Semantic Instance Segmentation of the Plasma Membrane of HeLa Cells
por: Karabağ, Cefa, et al.
Publicado: (2021)

A Novel Focal Phi Loss for Power Line Segmentation with Auxiliary Classifier U-Net
por: Jaffari, Rabeea, et al.
Publicado: (2021)

VEGF(165)b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy
por: Varey, A H R, et al.
Publicado: (2008)

Impact of Training Data, Ground Truth and Shape Variability in the Deep Learning-Based Semantic Segmentation of HeLa Cells Observed with Electron Microscopy
por: Karabağ, Cefa, et al.
Publicado: (2023)

Detection of VEGF-A(xxx)b Isoforms in Human Tissues
por: Bates, David O., et al.
Publicado: (2013)

Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior
por: Yamamoto, Hideki, et al.
Publicado: (2016)

Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes
por: Marks, Edward C. A., et al.
Publicado: (2018)

Visualisation and Analysis of Speech Production with Electropalatography
por: Verhoeven, Jo, et al.
Publicado: (2019)

VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals
por: Yamakuchi, Munekazu, et al.
Publicado: (2023)

Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents
por: Mineur, Pierre, et al.
Publicado: (2007)

Digital pathology: 15th European congress, ECDP 2019, Warwick, UK, april 10-13, 2019, proceedings
por: Reyes-Aldasoro, Constantino Carlos, et al.
Publicado: (2019)

Macrosight: A Novel Framework to Analyze the Shape and Movement of Interacting Macrophages Using Matlab(®) †
por: Solís-Lemus , José Alonso, et al.
Publicado: (2019)

Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury
por: Medford, Andrew RL, et al.
Publicado: (2009)

Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2
por: Peach, Chloe J., et al.
Publicado: (2018)

Zebrafish Recoverin Isoforms Display Differences in Calcium Switch Mechanisms
por: Elbers, Dana, et al.
Publicado: (2018)

Morphological Estimation of Cellularity on Neo-Adjuvant Treated Breast Cancer Histological Images
por: Ortega-Ruiz, Mauricio Alberto, et al.
Publicado: (2020)

Use of horseradish peroxidase for gene-directed enzyme prodrug therapy with paracetamol
por: Tupper, J, et al.
Publicado: (2004)

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis
por: Vempati, Prakash, et al.
Publicado: (2011)

VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164(b) therapy
por: Cromer, Walter E, et al.
Publicado: (2013)

Current Limitations of Murine Models in Oncology for Ascorbate Research
por: Campbell, Elizabeth J., et al.
Publicado: (2014)

IL-1 drives breast cancer growth and bone metastasis in vivo
por: Holen, Ingunn, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8rsq4kl4hjq99sg596idrd2ugt