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Effectiveness of Gefitinib against Non–Small-Cell Lung Cancer with the Uncommon EGFR Mutations G719X and L861Q

INTRODUCTION: In non–small-cell lung cancer, an exon 19 deletion and an L858R point mutation in the epidermal growth factor receptor (EGFR) are predictors of a response to EGFR-tyrosine kinase inhibitors. However, it is uncertain whether other uncommon EGFR mutations are associated with sensitivity...

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Detalles Bibliográficos
Autores principales: Watanabe, Satoshi, Minegishi, Yuji, Yoshizawa, Hirohisa, Maemondo, Makoto, Inoue, Akira, Sugawara, Shunichi, Isobe, Hiroshi, Harada, Masao, Ishii, Yoshiki, Gemma, Akihiko, Hagiwara, Koichi, Kobayashi, Kunihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132025/
https://www.ncbi.nlm.nih.gov/pubmed/24419415
http://dx.doi.org/10.1097/JTO.0000000000000048