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Effectiveness of Gefitinib against Non–Small-Cell Lung Cancer with the Uncommon EGFR Mutations G719X and L861Q
INTRODUCTION: In non–small-cell lung cancer, an exon 19 deletion and an L858R point mutation in the epidermal growth factor receptor (EGFR) are predictors of a response to EGFR-tyrosine kinase inhibitors. However, it is uncertain whether other uncommon EGFR mutations are associated with sensitivity...
Autores principales: | Watanabe, Satoshi, Minegishi, Yuji, Yoshizawa, Hirohisa, Maemondo, Makoto, Inoue, Akira, Sugawara, Shunichi, Isobe, Hiroshi, Harada, Masao, Ishii, Yoshiki, Gemma, Akihiko, Hagiwara, Koichi, Kobayashi, Kunihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132025/ https://www.ncbi.nlm.nih.gov/pubmed/24419415 http://dx.doi.org/10.1097/JTO.0000000000000048 |
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