Clinical Significance of BIM Deletion Polymorphism in Non–Small-Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation

BACKGROUND: Germline alterations in the proapoptotic protein Bcl-2–like 11 (BIM) can have a crucial role in tumor response to treatment. To determine the clinical utility of detecting BIM deletion polymorphism in non–small-cell lung cancer positive for epidermal growth factor receptor (EGFR) mutatio...

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Detalles Bibliográficos
Autores principales: Isobe, Kazutoshi, Hata, Yoshinobu, Tochigi, Naobumi, Kaburaki, Kyohei, Kobayashi, Hiroshi, Makino, Takashi, Otsuka, Hajime, Sato, Fumitomo, Ishida, Fumiaki, Kikuchi, Naoshi, Hirota, Nao, Sato, Keita, Sano, Go, Sugino, Keishi, Sakamoto, Susumu, Takai, Yujiro, Shibuya, Kazutoshi, Iyoda, Akira, Homma, Sakae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132037/
https://www.ncbi.nlm.nih.gov/pubmed/24736070
http://dx.doi.org/10.1097/JTO.0000000000000125

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