A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

INTRODUCTION: Detection of the ALK rearrangement in a solid tumor gives these patients the option of crizotinib as an oral form of anticancer treatment. The current test of choice is fluorescence in situ hybridization (FISH), but various cheaper and more convenient immunohistochemical (IHC) assays h...

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Detalles Bibliográficos
Autores principales: Le Quesne, John, Maurya, Manisha, Yancheva, Slaveya G., O’Brien, Mary, Popat, Sanjay, Wotherspoon, Andrew C., de Castro, David Gonzalez, Nicholson, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132045/
https://www.ncbi.nlm.nih.gov/pubmed/24787965
http://dx.doi.org/10.1097/JTO.0000000000000157

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