Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies

AIMS: The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain. METHODS: We conducted a cross-sectional, descriptive, multicenter study involving 109 patients with Alzheimer's disease (AD) and 59 with...

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Autores principales: Sarabia-Cobo, Carmen María, Pérez, Victoria, Hermosilla, Carmen, Nuñez, María José, de Lorena, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132252/
https://www.ncbi.nlm.nih.gov/pubmed/25177331
http://dx.doi.org/10.1159/000363227
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author Sarabia-Cobo, Carmen María
Pérez, Victoria
Hermosilla, Carmen
Nuñez, María José
de Lorena, Pablo
author_facet Sarabia-Cobo, Carmen María
Pérez, Victoria
Hermosilla, Carmen
Nuñez, María José
de Lorena, Pablo
author_sort Sarabia-Cobo, Carmen María
collection PubMed
description AIMS: The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain. METHODS: We conducted a cross-sectional, descriptive, multicenter study involving 109 patients with Alzheimer's disease (AD) and 59 with mild cognitive impairment (MCI). RESULTS: The older group with AD had a higher prevalence of leukoaraiosis and apathy, with significant differences compared to the MCI group. CONCLUSIONS: To our knowledge, this is the first multicenter study in our country that jointly analyzes the presence of apathy and leukoaraiosis in the institutionalized elderly with varying degrees of cognitive impairment according to the most recent criteria for detecting apathy in dementia.
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spelling pubmed-41322522014-08-29 Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies Sarabia-Cobo, Carmen María Pérez, Victoria Hermosilla, Carmen Nuñez, María José de Lorena, Pablo Dement Geriatr Cogn Dis Extra Original Research Article AIMS: The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain. METHODS: We conducted a cross-sectional, descriptive, multicenter study involving 109 patients with Alzheimer's disease (AD) and 59 with mild cognitive impairment (MCI). RESULTS: The older group with AD had a higher prevalence of leukoaraiosis and apathy, with significant differences compared to the MCI group. CONCLUSIONS: To our knowledge, this is the first multicenter study in our country that jointly analyzes the presence of apathy and leukoaraiosis in the institutionalized elderly with varying degrees of cognitive impairment according to the most recent criteria for detecting apathy in dementia. S. Karger AG 2014-07-01 /pmc/articles/PMC4132252/ /pubmed/25177331 http://dx.doi.org/10.1159/000363227 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Original Research Article
Sarabia-Cobo, Carmen María
Pérez, Victoria
Hermosilla, Carmen
Nuñez, María José
de Lorena, Pablo
Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title_full Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title_fullStr Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title_full_unstemmed Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title_short Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies
title_sort apathy and leukoaraiosis in mild cognitive impairment and alzheimer's disease: multicenter diagnostic criteria according to the latest studies
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132252/
https://www.ncbi.nlm.nih.gov/pubmed/25177331
http://dx.doi.org/10.1159/000363227
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