Vitamin C Protected Human Retinal Pigmented Epithelium from Oxidant Injury Depending on Regulating SIRT1

The purpose was to investigate the protective effects of Vitamin C (Vit C) and the regulatory mechanism between Vit C and sirtuin 1 (SIRT1) in PREs during oxidative stress as Vit C and SIRT1 exerted famous effects as antioxidants. We found that moderate Vit C (100 µM) prevented ARPE-19 cells from da...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Li, Langen, Zhang, Yufeng, Geriletu, Yang, Jia, Zhang, Yanmei, Xing, Yiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132313/
https://www.ncbi.nlm.nih.gov/pubmed/25147862
http://dx.doi.org/10.1155/2014/750634

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