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A dimeric state for PRC2

Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) can recruit PRC2 to chromatin. Previous studies identified PRC2 subunits in a complex with the apparent molecular weight of a dimer, whi...

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Detalles Bibliográficos
Autores principales:	Davidovich, Chen, Goodrich, Karen J., Gooding, Anne R., Cech, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Molecular Biology - NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132707/ https://www.ncbi.nlm.nih.gov/pubmed/24992961 http://dx.doi.org/10.1093/nar/gku540

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