Embryonic stem cell-specific microRNAs contribute to pluripotency by inhibiting regulators of multiple differentiation pathways

The findings that microRNAs (miRNAs) are essential for early development in many species and that embryonic miRNAs can reprogram somatic cells into induced pluripotent stem cells suggest that these miRNAs act directly on transcriptional and chromatin regulators of pluripotency. To elucidate the tran...

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Detalles Bibliográficos
Autores principales: Gruber, Andreas J., Grandy, William A., Balwierz, Piotr J., Dimitrova, Yoana A., Pachkov, Mikhail, Ciaudo, Constance, van Nimwegen, Erik, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132708/
https://www.ncbi.nlm.nih.gov/pubmed/25030899
http://dx.doi.org/10.1093/nar/gku544

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