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In vitro selection of DNA-cleaving deoxyribozyme with site-specific thymidine excision activity

Single-nucleotide polymorphisms, either inherited or due to spontaneous DNA damage, are associated with numerous diseases. Developing tools for site-specific nucleotide modification may one day provide a way to alter disease polymorphisms. Here, we describe the in vitro selection and characterizatio...

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Detalles Bibliográficos
Autores principales:	Wang, Mingqi, Zhang, Huafan, Zhang, Wei, Zhao, Yongyun, Yasmeen, Afshan, Zhou, Li, Yu, Xiaoqi, Tang, Zhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132718/ https://www.ncbi.nlm.nih.gov/pubmed/25030901 http://dx.doi.org/10.1093/nar/gku592

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