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The effect of Pot1 binding on the repair of thymine analogs in a telomeric DNA sequence

Telomeric DNA can form duplex regions or single-stranded loops that bind multiple proteins, preventing it from being processed as a DNA repair intermediate. The bases within these regions are susceptible to damage; however, mechanisms for the repair of telomere damage are as yet poorly understood. W...

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Detalles Bibliográficos
Autores principales: Theruvathu, Jacob A., Darwanto, Agus, Hsu, Chia Wei, Sowers, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132724/
https://www.ncbi.nlm.nih.gov/pubmed/25053838
http://dx.doi.org/10.1093/nar/gku602